Daphne  is a filmmaker born and raised in Staten Island, NY.  She was raised by her West Indian parents in a house with her seven brothers and sisters, two dogs, one cat and one bathroom. 

Daphne's  career first began in front of the camera as a child actor and then behind it as a producer of commercials and music videos for such artists as Blues Traveler, the Notorious B.I.G., and Queen Latifah. 

When hired to produce the Academy Award–nominated  4 Little Girls, directed by Spike Lee, a documentary about the murder of four African American girls in the 16th Street Baptist Church bombing in Birmingham, Alabama, in 1963.  The experience impacted her life and changed her career path; documentary filmmaking became her passion.

Since that time, she has worked on the films Feels Like Coming Home (dir. Martin Scorsese); Warming by the Devils Fire (dir. Charles Burnett); The Curious Case of Curt Flood (dir. Spike Lee, 2011); Slavery by Another Name (dir. Samuel D. Pollard, 2012); and Maynard (dir. Samuel D. Pollard, 2017), among many others. In 2016, Daphne McWilliams’s directorial debut, In a Perfect World... premiered on Showtime.